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Agri : Agri (Algoloji) Dernegi'nin... Jan 2021Dermoscopic examination is a very effective and practical method that significantly reduces the need for invasive diagnostic procedures in many skin diseases....
Dermoscopic examination is a very effective and practical method that significantly reduces the need for invasive diagnostic procedures in many skin diseases. Dermoscopic features of many cutaneous conditions have been well described, however, only one single case report has defined dermoscopic features of notalgia paresthetica so far. The clinical presentation of this entity can mimic many dermatological conditions including lichen simplex chronicus, cutaneous amyloidosis, and tinea versicolor. We tried to identify dermoscopic findings of the notalgia paresthetica, aiming to facilitate the diagnosis.
Topics: Amyloidosis, Familial; Humans; Paresthesia; Peripheral Nervous System Diseases; Pruritus; Skin Diseases, Genetic
PubMed: 34254657
DOI: 10.14744/agri.2020.80106 -
Skin Therapy Letter 2004Ciclopirox (Loprox) is a broad-spectrum antifungal medication that also has antibacterial and anti-inflammatory properties. Its main mode of action is thought to be its... (Review)
Review
Ciclopirox (Loprox) is a broad-spectrum antifungal medication that also has antibacterial and anti-inflammatory properties. Its main mode of action is thought to be its high affinity for trivalent cations, which inhibit essential co-factors in enzymes. Clinical trials have shown that ciclopirox gel is a successful treatment for seborrheic dermatitis of the scalp as well as for tinea pedis. Adverse effects are generally mild and include a skin-burning sensation, contact dermatitis, and pruritus. Ciclopirox is indicated in the US for the treatment of tinea pedis, tinea corporis, pityriasis versicolor, seborrheic dermatitis, and cutaneous candidiasis.
Topics: Administration, Topical; Antifungal Agents; Canada; Ciclopirox; Dermatomycoses; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gels; Humans; Male; Prognosis; Pyridones; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome
PubMed: 15334276
DOI: No ID Found -
Revista Da Associacao Medica Brasileira... 2012To evaluate and compare the efficacy of topical antifungal drugs applied to the treatment of each dermatomycosis. (Meta-Analysis)
Meta-Analysis Review
OBJECTIVE
To evaluate and compare the efficacy of topical antifungal drugs applied to the treatment of each dermatomycosis.
METHODS
A systematic review of randomized clinical trials, published in Portuguese, Spanish and English until July 2010, which compared the use of azole and allylamine antifungal drugs among themselves and with placebo in the treatment of cutaneous candidiasis and T. versicolor, T. pedis, T. cruris and T. corporis was performed. The efficacy outcomes evaluated were mycological cure at the end of treatment and sustained cure.
RESULTS
Of the 4,424 studies initially identified, 49 met the selection criteria and were included in the meta-analyses. The grouped efficacy data evidenced the superiority of antifungal drugs compared to placebo, regardless of the dermatomycosis under evaluation, with odds ratio values ranging from 2.05 (95% CI 1.18-3.54) to 67.53 (95% CI 11.43-398.86). Allylamines were better than azoles only for the outcome sustained cure (OR 0.52 [95% CI 0.31-0.89]).
CONCLUSION
There is consistent evidence of the superiority of antifungal drugs over the use of placebo, and placebo-controlled studies are no longer justifiable. Allylamines maintain the mycological cure for longer periods compared to azole drugs. Given the significant cost difference among the classes, pharmacoeconomic analyses should be performed.
Topics: Administration, Cutaneous; Antifungal Agents; Candidiasis, Cutaneous; Humans; Randomized Controlled Trials as Topic; Tinea; Treatment Outcome
PubMed: 22735222
DOI: No ID Found -
Turkish Journal of Medical Sciences Jun 2020H. pylori has been found to be related to certain dermatological diseases. However, there is no data as yet to propose an association between H. pylori and pityriasis...
BACKGROUND/AIM
H. pylori has been found to be related to certain dermatological diseases. However, there is no data as yet to propose an association between H. pylori and pityriasis versicolor. In this study, we aimed to evaluate the association between H. pylori and pityriasis versicolor.
MATERIALS AND METHODS
This was a prospective study performed in the Gastroenterology and Dermatology and Venereology departments of the Health Sciences University, Ankara Training and Research Centre. A total of 57 consecutive patients (27 pityriasis versicolor, 30 telogen effluvium) were enrolled from the Department of Dermatology and Venereology. All patients were screened for H. pylori IgG and CagA. In addition, urea breath test was carried out to detect the existence of H. pylori infection.
RESULTS
There were significantly higher rates of H. pylori positivity, H. pylori IgG in serum in the pityriasis versicolor group compared to the telogen effluvium group (P < 0.05). In addition, the number of patients with dyspeptic complaints was higher in the pityriasis versicolor group than in the telogen effluvium group. The odds ratio for dyspepsia, H. pylori positivity, and H. pylori IgG were 2.48, 1.67, and 1.78, respectively.
CONCLUSION
In this study, we found a statistically significant relationship between H. pylori infection and pityriasis versicolor. Therefore, H. pylori eradication could be considered in recurrent pityriasis versicolor patients with dyspepsia. New studies are required to clarify the effect of eradication treatment on the clinical course of pityriasis versicolor.
Topics: Adult; Breath Tests; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Prospective Studies; Tinea Versicolor
PubMed: 32151117
DOI: 10.3906/sag-1910-48 -
Journal of Clinical and Diagnostic... Aug 2017Pityriasis Versicolor (PV) is a common health problem caused by genus , a lipophilic fungi found as a part of the normal flora of skin. Although PV is common in Egypt,...
INTRODUCTION
Pityriasis Versicolor (PV) is a common health problem caused by genus , a lipophilic fungi found as a part of the normal flora of skin. Although PV is common in Egypt, there is little information regarding the species distribution in PV patients to date.
AIM
To spot a light on the distribution and clinico-epidemiological features of the species in PV patients and healthy individuals that were established by conventional phenotypic and molecular techniques.
MATERIALS AND METHODS
A cross-sectional study including 167 individuals; 137 clinically suspected PV patients attending Mansoura University Hospitals, Egypt and 30 healthy control individuals, was carried out. Characterization of species was performed phenotypically by conventional, culture-based methods and biochemical tests. Genomic DNA was extracted from isolated colonies for PCR amplification of the highly conserved 26S rDNA region with further species level identification by Restriction Fragment Length Polymorphism (RFLP) using Hha1 and BstC1 enzymes. The association of species with epidemiological profile and clinical characteristics was studied.
RESULTS
A 94.2% of PV samples and 13.3% of control samples were positive by Potassium Hydroxide (KOH) while 71.5% of PV samples and 16.7% of control samples yielded growth in culture with high statistically significant differences (p=0.0001, for both methods). By phenotypic methods, only 75.5% of isolates from patients were identified as: (51.4%), , (29.7%), (13.5%) and (5.4%) while by RFLP technique, six species were revealed: (44.9%), (24.5%), (12.2 %), (10.2%), (4.1%) and (4.1%). Most species were isolated from hypopigmented lesions of PV patients aged between 20-29 years. Neck and back were the most common affected sites. Only (10%) and (6.7%) were identified in healthy controls.
CONCLUSION
and are the commonly encountered species in both healthy and diseased human skin although other species were identified in PV patients. PCR-RFLP method represents a considerably accurate technique in identification of different species for better understanding of their effect on the clinico-epidemiological characterization of PV patients in Egypt.
PubMed: 28969121
DOI: 10.7860/JCDR/2017/27747.10416 -
CMAJ : Canadian Medical Association... Jul 2014
Topics: Atrophy; Diagnosis, Differential; Humans; Malassezia; Male; Middle Aged; Skin; Tinea Versicolor
PubMed: 24733760
DOI: 10.1503/cmaj.131846 -
Nihon Ishinkin Gakkai Zasshi = Japanese... 1999Pityriasis versicolor and malassezia folliculitis were studied clinically and mycologically. The main results were as follows: 1) The average age of pityriasis... (Review)
Review
Pityriasis versicolor and malassezia folliculitis were studied clinically and mycologically. The main results were as follows: 1) The average age of pityriasis versicolor patients has gradually become higher. 2) Negative rates of Malassezia furfur after treatment were very high by direct examination but relatively low by culture. 3) Patients who were negative by culture on completion of treatment seldom recurred within 2 months. 4) We can evaluate the effectiveness of antifungal application by using Malassezia furfur as normal skin flora on the volunteer's back. 5) Malassezia furfur (orbiculare or ovale type) is detected in follicular contents of steroid acne and acne vulgaris, which makes it necessary to establish criteria for diagnosis of malassezia folliculitis.
Topics: Aged; Folliculitis; Humans; Malassezia; Middle Aged; Tinea Versicolor
PubMed: 10234076
DOI: 10.3314/jjmm.40.69 -
Journal of Fungi (Basel, Switzerland) Nov 2022Onychomycosis is a fungal disease of the nail that is found worldwide and is difficult to diagnose accurately. This study used metagenomics to investigate the...
Onychomycosis is a fungal disease of the nail that is found worldwide and is difficult to diagnose accurately. This study used metagenomics to investigate the microbiology of 18 clinically diagnosed mycotic nails and two normal nails for fungi and bacteria using the ITS2 and 16S loci. Four mycotic nails were from Bass Coast, six from Melbourne Metropolitan and eight from Shepparton, Victoria, Australia. The mycotic nails were photographed and metagenomically analysed. The ITS2 sequences for and averaged over 90% of hits in 14/18 nails. The high abundance of sequences of a single dermatophyte, compared to all other fungi in a single nail, made it the most likely infecting agents (MLIA). and interdigitale/mentagrophytes were found in Bass Coast and Shepparton while only was found in Melbourne. Two nails with mixed with high abundance non-dermatophyte moulds (NDMs) (, ) were also observed. The two control nails contained chiefly and . For bacteria, was in every nail and was the most abundant, including the control nails, with an overall mean rate of 66.01%. , , and also featured.
PubMed: 36422019
DOI: 10.3390/jof8111198 -
Polish Journal of Microbiology Dec 2022Seventy-seven strains of were included in this study. Biofilm and hydrolytic enzyme production were studied by using specific solid media. The Real-Time reverse...
Seventy-seven strains of were included in this study. Biofilm and hydrolytic enzyme production were studied by using specific solid media. The Real-Time reverse transcriptase qPCR method was applied to determine the overexpression of genes encoding the extracellular enzymes. All included species produced biofilms. No statistically significant difference was observed between species in biofilm formation ( = 0.567). All species produced lipase, and 95% of showed a strong enzymatic activity (Pz = 0.55 ± 0.02). A statistically significant difference was observed between the mean keratinase indices of and the other species ( = 0.005). The overexpression of one or more genes was observed in 100% of strains isolated from patients with folliculitis, 87.5% - with pityriasis versicolor, and 57.14% of the control group isolates. A statistically significant difference in the lipase gene expression ( = 0.042) was between the strains from patients with folliculitis and the control group. This investigation provides more information about the frequency of the production of the major enzymes considered virulence factors of species. Interestingly, the overexpression of one or more genes was observed in strains isolated from patients with disorders.
Topics: Humans; Malassezia; Virulence Factors; Tinea Versicolor; Lipase; Folliculitis
PubMed: 36473111
DOI: 10.33073/pjm-2022-047 -
Anais Brasileiros de Dermatologia 2017Superficial mycoses are fungal infections restricted to the stratum corneum and to the hair shafts, with no penetration in the epidermis; they are: white piedra, black...
Superficial mycoses are fungal infections restricted to the stratum corneum and to the hair shafts, with no penetration in the epidermis; they are: white piedra, black piedra, tinea versicolor, and tinea nigra. This study presents images of mycological tests performed in the laboratory, as well as exams performed at the authors office, in order to improve the dermatologist's knowledge about the diagnosis of these dermatoses, which are common in many countries.
Topics: Humans; Piedra; Tinea
PubMed: 29186263
DOI: 10.1590/abd1806-4841.20176018